00604nam a22001337a 4500020002200000020002000022082001600042100002600058245005700084260006200141300004000203500006400243650016300307  a979818474505 (hb)  a8181474503 (hb)  a615.19bSIL  aSilverman, Richard B.10aThe organic chemistry of drug design and drug action  aCalifornia bAcademic Press an Imprint of Elsevier c2004  axix, 617 p.b: ill., Col.c; 24 cm.  aIncludes bibliographical  references, appendices and index.  aOrganic chemistryvMedicinal chemistryvDrug designvDrug actionvPharmacophore modelingvPharmacophore modelingvDrug metabolismvMolecular recognitionvRIPS